Korean Circ J.  1993 Dec;23(6):814-819. 10.4070/kcj.1993.23.6.814.

A Case of Refractory Variant Angina Relieved by Clonidine

• Jeon IM
• Won SY
• Jeong JW
• Park YK
• Park OK

• KMID: 2229266
• DOI: http://doi.org/10.4070/kcj.1993.23.6.814

Abstract

Coronary spasm may be induced by a variety of physiologic and pharmacologic stimuli but specific receptor blockade has not been consistently shown to prevent the attacks. Most patients with variant angina respond well to treatment with calcium antagonists and nitrates. A small proportion of patients are refractory to this therapy. We report a case of the patient with a 9-year-history of variant angina who has been refractory to high doses of calcium antagonists and nitrates. The repeated addition of clonidine was consistently effective in abolishing both symptoms and objective evidence of myocardial ischemia in this particular patient.

Keyword

Variant angina; Coronary Spasm

MeSH Terms

Calcium
Clonidine*
Humans
Myocardial Ischemia
Nitrates
Spasm
Calcium
Clonidine
Nitrates