Korean J Crit Care Med.  2012 Nov;27(4):230-236. 10.4266/kjccm.2012.27.4.230.

Gender Differences in Patients with Acute Myocardial Infarction Undergoing Percutaneous Coronary Intervention

• Hahn S

• KMID: 2227950
• DOI: http://doi.org/10.4266/kjccm.2012.27.4.230

Abstract

BACKGROUND
Limited data are available for gender-based differences among patients with acute myocardial infarction (AMI) undergoing coronary revascularization in Korea. The purpose of this study is to identify gender-based differences in clinical characteristics, risk factors and outcomes among Korean patients undergoing percutaneous coronary intervention (PCI).
METHODS
Patients with AMI undergoing PCI between Jan 2009 and Sep 2011 were included (n = 457) in the study. Clinical characteristics and cardiovascular risk factors as well as major adverse cardiac events (MACE), including death after PCI, were compared between women (n = 134) and men (n = 323).
RESULTS
Women were older (69.8 +/- 10.7 vs. 60.0 +/- 11.7 years, p < .001) and had more comorbidities, such as diabetes (44.0% vs. 32.8%, p = .025) and hypertension (64.9% vs. 48.9%, p = .002) compared to men. Women were less likely to have a smoking history (p < .001). There were no significant differences in all causes of death and in MACE between women and men. By the multivariate analysis, age, HDL-cholesterol and left ventricle ejection fraction are associated with mortality and MACE.
CONCLUSIONS
In this study, women did not emerge as an independent predictor for MACE; however, they were older and had a higher incidence of hypertension and diabetes than men.

Keyword

angioplasty; comorbidity; gender; mortality; myocardial infarction

MeSH Terms

Angioplasty
Cause of Death
Comorbidity
Female
Heart Ventricles
Humans
Hypertension
Incidence
Korea
Male
Multivariate Analysis
Myocardial Infarction
Percutaneous Coronary Intervention
Risk Factors
Smoke
Smoking
Smoke