Korean Circ J.
2003 Dec;33(12):1155-1160. 10.4070/kcj.2003.33.12.1155.
Familial Sick Sinus Syndrome
- Affiliations
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- 1Department of Internal Medicine, Kyung Hee University Medical School, Seoul, Korea.
- 2Department of Internal Medicine, Sejong General Hospital, Bucheon, Korea.
- KMID: 2227248
- DOI: http://doi.org/10.4070/kcj.2003.33.12.1155
Abstract
- This paper presents a family with sick sinus syndrome, spanning three generations and with an autosomal dominant trait. The proband was affected by atrial fibrillation with a slow ventricular rhythm that required a permanent pacemaker. Her three sons were affected with a sinus node dysfunction and one daughter died suddenly at the age of 32 years. A pacemaker was implanted in the proband and her two sons with symptoms related to bradycardia. One of her sons with the pacemaker died of a cerebrovascular accident several months later. We report a family with sick sinus syndrome requiring the implantation of a pacemaker with a review of the literature.
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