Korean Circ J.
2005 Dec;35(12):904-909. 10.4070/kcj.2005.35.12.904.
Lesion Characteristics of Mitral Valve Prolapse due to Myxomatous Degeneration in Korea: A Prospective Multicenter Study Using Echocardiography
- Affiliations
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- 1Division of Cardiology, Asan Medical Center, Seoul, Korea. jksong@amc.seoul.kr
- 2Kyungpook University Hospital, Daegu, Korea.
- 3Kyunghee University Hospital, Seoul, Korea.
- 4Keimyung University Hospital, Daegu, Korea.
- 5Korea University Hospital, Seoul, Korea.
- 6Wonkwang University Hospital, Iksan, Korea.
- 7Chonnam National University Hospital, Gwangju, Korea.
- 8Chosun University Hospital, Gwangju, Korea.
- 9Chungnam National University Hospital, Daejeon, Korea.
- 10Catholic University Hospital, Seoul, Korea.
- 11Samsing Medical Center, Seoul, Korea.
- 12Yonsei Medical Center, Seoul, Korea.
- 13Seoul National University, Seoul, Korea.
- KMID: 2227132
- DOI: http://doi.org/10.4070/kcj.2005.35.12.904
Abstract
- BACKGROUND AND OBJECTIVES
We sought to characterize the lesion characteristics of mitral valve prolapse (MVP), which is being increasingly recognized as a cause of mitral regurgitation (MR) in Koreans
SUBJECTS AND METHODS
497 Patients with MVP that was diagnosed by echocardiography in 13 university-affiliated hospitals from Jan to Dec 2003 were prospectively enrolled in our study.
RESULTS
A total of 497 patients (270 males, 54%) were enrolled and their mean age was 52+/-17 years. Grade 4 MR was present in 272 patients (54.7%); grade 3, 2 and 1 MR as present in 30.2%, 10.7% and 4.2%, respectively. MVP of the anterior and posterior mitral leaflet was present in 170 patients (34.2%) and 223 patients (44.9%), respectively; MVP developed in both leaflets in 104 patients (20.9%). In 37 patients (7.4%), MVP developed in all 6 segments of the mitral leaflet and these patients were younger (37+/-14 versus 54+/-16 years, respectively, p<0.05) and had a lower prevalence of chordae rupture and severe MR compared to the other patients. Among the 266 mitral segments showing prolapse in the 132 patients (26.6%) who underwent transesophageal echocardiography, the posterior medial scallop was the most frequently diseased one (26%), and this was followed by the posterior middle scallop (18%), the medial (17%), lateral (14%) and middle (13%) part of the anterior leaflet, and the posterior lateral scallop (12%). Younger patients with a mean age <45 years showed a lower prevalence of single segment prolapse, hypertension, severe MR and chordae rupture compared to the older patients (p<0.001, each).
CONCLUSION
The medial part of both mitral leaflets was the predilection site for the development of MVP in Koreans and the lesion characteristics were different according to the patients' age.
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Cited by 1 articles
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Massive Hemoptysis due to Acute Mitral Regurgitation with Sporadic Primary Mitral Valve Prolapse
Won Young Chae, Sun Jin Park, Chi Woo Song, Byoung Hoon Lee, Sang Hoon Kim, Jae Hyung Lee
Korean J Crit Care Med. 2015;30(3):202-206. doi: 10.4266/kjccm.2015.30.3.202.
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