Korean Circ J.  2008 Aug;38(8):432-435. 10.4070/kcj.2008.38.8.432.

A Case of In-Stent Plaque Rupture Presenting as an Acute Myocardial Infarction

Affiliations
  • 1Department of Internal Medicine and Ewha Medical Research Institute, School of Medicine, Ewha Womans University, Seoul, Korea. pseongh@ewha.ac.kr

Abstract

In-stent atheromatous plaque rupture is a very rare event. A 51-year-old man presented with an acute inferior myocardial infarction 9 years after bare-metal stent implantation in the mid-portion of right coronary artery. After thrombolytic therapy, coronary angiography and intravascular ultrasound (IVUS) revealed a ruptured plaque at the mid portion of the stented segment.

Keyword

Stent; Atheroma; Rupture; Intravascular ultrasonography

MeSH Terms

Coronary Angiography
Coronary Vessels
Humans
Inferior Wall Myocardial Infarction
Middle Aged
Myocardial Infarction
Plaque, Atherosclerotic
Rupture
Stents
Thrombolytic Therapy
Ultrasonography, Interventional

Figure

  • Fig. 1 Angiogram of the right coronary artery. A, B: the initial coronary angiogram revealed a wedged shape intraluminal filling defect in the stent area. C, D: successful reperfusion was achieved after stenting.

  • Fig. 2 Cross-sectional intravascular ultrasound images of the RCA. A: the initial IVUS images showed ruptured plaque (white arrow). B: the post IVUS examination revealed adequate expansion and apposition without complication.


Reference

1. Weintraub WS. The pathophysiology and burden of restenosis. Am J Cardiol. 2007. 100:3K–9K.
2. Forrester JS. Toward understanding the evolution of plaque rupture: correlating vascular pathology with clinical outcomes. J Am Coll Cardiol. 2003. 42:1566–1568.
3. Hong BK, Cho SY, Jang YS, et al. Intravascular ultrasound imaging in patient with acute myocardial infarction. Korean Circ J. 1998. 28:931–938.
4. Okura H, Taguchi H, Kubo T, et al. Atherosclerotic plaque with ultrasonic attenuation affects coronary reflow and infarct size in patients with acute coronary syndrome: an intravascular ultrasound study. Circ J. 2007. 71:648–653.
5. Hur SH, Hassan AH, Rekhi R, et al. Serial intravascular ultrasonic study of outcomes of coronary culprit lesions with plaque rupture following bare metal stent implantation in patients with angina pectoris. Am J Cardiol. 2007. 99:1394–1398.
6. Hong YJ, Jeong MH, Hyun DW, et al. Impact of preinterventional arterial remodeling on in-stent neointimal hyperplasia and in-stent restenosis after coronary stent implantation. Circ J. 2005. 69:414–419.
7. Hoffmann R, Mintz GS, Dussaillant GR, et al. Patterns and mechanisms of in-stent restenosis: a serial intravascular ultrasound study. Circulation. 1996. 94:1247–1254.
8. Feres F, Costa JR Jr, Abizaid A. Very late thrombosis after drug-eluting stents. Catheter Cardiovasc Interv. 2006. 68:83–88.
9. Cutlip DE, Baim DS, Ho KK, et al. Stent thrombosis in the modern era: a pooled analysis of multicenter coronary stent trials. Circulation. 2001. 103:1967–1971.
10. Nallamothu BK, Blaney ME, Morris SM, et al. Acute reperfusion therapy in ST-elevation myocardial infarction from 1994-2003. Am J Med. 2007. 120:693–699.
11. Gavaliatsis IP. From thrombolysis to thrombogenesis in clinical practice: coronary ruptures plaque angiography. Int J Cardiol. 1996. 55:103–105.
12. Scott NA. Restenosis following implantation of bare metal coronary stents: pathophysiology and pathways involved in the vascular response to injury. Adv Drug Deliv Rev. 2006. 58:358–376.
13. Hong MK. Medical treatments to prevent in-stent restenosis. Korean Circ J. 1999. 29:353–356.
Full Text Links
  • KCJ
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr