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Korean J Clin Neurophysiol.  2015 Jun;17(1):24-27. 10.14253/kjcn.2015.17.1.24.

Myeloma-associated Amyloidosis Presenting as Orthostatic Intolerance

Affiliations
  • 1Department of Neurology, Institute of Health Science, Gyeongsang National University School of Medicine, Jinju, Korea. pkjong@gnu.ac.kr

Abstract

Amyloidosis is a systemic disorder associated with clonal plasma cell dyscrasia. Nephrotic syndrome, congestive heart failure, autonomic and peripheral neuropathy is often associated features in amyloidosis. Early diagnosis is most important because of different prognosis by stage. The diagnosis can be delayed since symptoms of amyloidosis may vary or nonspecific. We describe a patient of myeloma-associated amyloidosis, who showed orthostatic intolerance as the first symptom of the disease.

Keyword

Orthostatic intolerance; Amyloidosis; Neuropathy

MeSH Terms

Amyloidosis*
Diagnosis
Early Diagnosis
Heart Failure
Humans
Nephrotic Syndrome
Orthostatic Intolerance*
Paraproteinemias
Peripheral Nervous System Diseases
Prognosis
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