J Rheum Dis.  2016 Apr;23(2):79-81. 10.4078/jrd.2016.23.2.79.

Effect of Tocilizumab on Serum Hepcidin and Anemia Response in Patients with Rheumatoid Arthritis

• Lee WS
• Yoo WH

• KMID: 2222782
• DOI: http://doi.org/10.4078/jrd.2016.23.2.79

Abstract

No abstract available.

MeSH Terms

Anemia*
Arthritis, Rheumatoid*
Hepcidins*
Humans

Figure

• 

  Figure 1. Hepcidin and anemia of chronic disease. Inflammation increases interleukin-6 production. The increase in hepcidin decreases macrophage iron release, intestinal iron absorption, and iron recycling in the bone marrow. Administering tocilizumab in a patient with rheumatoid arthritis has significant therapeutic implications regarding ameliorating anemia, inflammation, and abnormal iron metabolism.

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