Korean Diabetes J.  2009 Feb;33(1):48-57. 10.4093/kdj.2009.33.1.48.

A Nationwide Survey about the Current Status of Glycemic Control and Complications in Diabetic Patients in 2006: The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus

Affiliations
  • 1Department of Internal Medicine, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seoul, Korea.
  • 2Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, Korea.
  • 3Department of Internal Medicine, Kyung Hee University, East-West Neo Medical Center, Seoul, Korea.
  • 4Department of Internal Medicine, Uijeognbu St. Mary's Hospital, Catholic University Medical College, Uijeongbu, Korea.
  • 5Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.
  • 6Department of Internal Medicine, Cheju National University Hospital, Cheju National University School of Medicine, Jeju, Korea.
  • 7Department of Internal Medicine, Yeungnam University College of Medicine, Yeungnam University Hospital, Daegu, Korea.
  • 8Department of Internal Medicine, Pusan Paik Hospital, College of Medicine, Inje University, Busan, Korea.
  • 9Department of Internal Medicine, Chonbuk National University Hospital, Jeonju, Korea.
  • 10Department of Internal Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, Korea.
  • 11Department of Internal Medicine, Dongsan Hospital, Keimyung University School of Medicine, Daegu, Korea.
  • 12Department of Internal Medicine, St. Vincent's Hospital, Catholic University Medical College, Suwon, Korea.
  • 13Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. leei@knu.ac.kr

Abstract

BACKGROUND: The Committee of the Korean Diabetes Association on the Epidemiology of Diabetes Mellitus performed a nationwide survey about the current status of glycemic control and diabetic complications in 2006.
METHODS
The current study included 5,652 diabetic patients recruited from the rosters of endocrinology clinics of 13 tertiary hospitals in Korea. Age, gender, height, weight, waist circumference and blood pressure were investigated by standard method. Fasting and postprandial 2 hour glucose, glycosylated hemoglobin (HbA1c), lipid profiles, fasting insulin and c-peptide levels were measured. Microvascular (microalbuminuria, retinopathy and neuropathy) and macrovascular (coronary artery disease [CAD], cerebrovascular disease [CVD] and peripheral artery disease [PAD]) complications were reviewed in their medical records.
RESULTS
Mean age of total subjects was 58.7 (+/- 11.6) years and duration of diabetes was 8.8 (0~50) years. Mean fasting and postprandial 2 hour glucose levels were 145.9 +/- 55.0 and 208.0 +/- 84.4 mg/dL, respectively. Their mean HbA1c was 7.9 +/- 1.9%: the percentage of patients within target goal of glycemic control (< 7% of HbA1c) was 36.7%. In this study, 30.3%, 38.3% and 44.6% of patients was found to have microalbuminuria, retinopathy and nephropathy, respectively. Prevalence of CAD, CVD and PAD was 8.7%, 6.7% and 3.0%, respectively. Diabetic complications were closely related with age, duration of diabetes and glycemic control, and this relationship was stronger in microvascular complications than macrovascular ones.
CONCLUSION
Only about one third of patients with diabetes was found to reach target glycemic control in tertiary hospitals of Korea. More tight control is needed to reduce deleterious complications of diabetes in Korea.

Keyword

Diabetes complications; Diabetes mellitus; Human hemoglobin A1c protein

MeSH Terms

Arteries
Blood Pressure
C-Peptide
Diabetes Complications
Diabetes Mellitus
Endocrinology
Fasting
Glucose
Hemoglobin A, Glycosylated
Humans
Insulin
Korea
Medical Records
Peripheral Arterial Disease
Prevalence
Tertiary Care Centers
Waist Circumference
C-Peptide
Glucose
Hemoglobin A, Glycosylated
Insulin

Figure

  • Fig. 1 Glycemic control status evaluated by glycosylated hemoglobin (HbA1c) levels in total subjects.

  • Fig. 2 Prevalence of microvascular and macrovascular complications according to the duration of diabetes.

  • Fig. 3 Prevalence of microvascular and macrovascular complications of diabetes according to the HbA1c level.

  • Fig. 4 Prevalence of macrovascular complication by age groups and by durations of diabetes.


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