Clin Endosc.  2015 Jan;48(1):81-84. 10.5946/ce.2015.48.1.81.

Colonic Lymphangiomatosis Resolved after Excisional Biopsy

• Lee YS
• Kim GW
• Cho HJ
• Shim CS

• KMID: 2221765
• DOI: http://doi.org/10.5946/ce.2015.48.1.81

Abstract

Lymphangioma is an uncommon malformation of the lymphatic system that involves a benign proliferation of the lymphatics, with no established treatment method. Multiple colonic lymphangioma, or colonic lymphangiomatosis, is an extremely rare condition. We report a case of colonic lymphangiomatosis that was detected during a colonoscopic examination conducted as part of a general health check-up. The lesion completely resolved after excisional biopsy.

Keyword

Colon; Excision; Lymphangioma; Lymphangiomatosis; Resolution

MeSH Terms

Biopsy*
Colon*
Lymphangioma
Lymphatic System

Figure

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  Fig. 1 Colonoscopy revealing a cluster of multiple cystic masses of various sizes and shapes with the same color and surface as the surrounding normal mucosa.

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  Fig. 2 Abdominal computed tomography scan showing normal colonic findings.

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  Fig. 3 (A) Lifting solution is injected around the cystic masses. (B) A snare is applied to the injected cystic mass. (C) Shrunken mass after incision.

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  Fig. 4 (A) Hematoxylin and eosin staining of normal colonic mucosa and a markedly dilated lymphatic vessel (×100). (B) CD34 expression in a lymphatic vessel. Smooth muscle cells and endothelial cells are located beneath the colonic mucosal glands (×100). (C) D2-40 expression (brown color) in a lymphatic vessel (×200).

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  Fig. 5 Normal colonic mucosa is seen on third colonoscopy. No abnormality including previous lymphangiomatosis is found.

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