Ann Dermatol.  2009 May;21(2):168-170. 10.5021/ad.2009.21.2.168.

Cutaneous Sarcoidosis Presenting as Multiple Erythematous Macules and Patches

Affiliations
  • 1Department of Dermatology, Kangnam St. Mary`s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea. yymmpark6301@ hotmail.com

Abstract

Sarcoidosis is an idiopathic multisystemic disorder with variable cutaneous presentations that are classified as specific or non-specific according to the presence of non-caseating granulomas on histologic examination. Specific manifestations can include papules, scar sarcoidosis, ulcers, or even alopecia. Herein, we present a case of cutaneous sarcoidosis that presented as multiple erythematous macules and patches on the trunk and extremities of a 32-year-old man. The clinical appearance was unlike any other form reported in the literature.

Keyword

Cutaneous sarcoidosis; Macules; Patches

MeSH Terms

Adult
Alopecia
Cicatrix
Extremities
Granuloma
Humans
Sarcoidosis
Ulcer

Figure

  • Fig. 1 Multiple erythematous, slightly scaly macules and patches on the back (A), thigh (B), and right arm (C).

  • Fig. 2 (A) Histologic examination shows a well-circumscribed, non-caseating granuloma in the lower dermis (H&E, ×100). (B) The magnified view shows a multinucleated giant cell within the granuloma (H&E, ×400). (C) Reticulum staining reveals numerous granulomas containing fibers stained black by silver granules, surrounding and permeating the granulomas (Reticulum stain, ×400).


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Subcutaneous Sarcoidosis with Plantar Involvement
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Subcutaneous Sarcoidosis with Plantar Involvement
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Ann Dermatol. 2010;22(4):435-438.    doi: 10.5021/ad.2010.22.4.435.

Venous Leg Ulcer in a Sarcoidosis Patient: A Case Report
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Ann Dermatol. 2015;27(6):744-747.    doi: 10.5021/ad.2015.27.6.744.

Scar Sarcoidosis Developed after Blepharoplasty in Acute Lymphoblastic Leukemia Patient
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Ann Dermatol. 2017;29(4):511-513.    doi: 10.5021/ad.2017.29.4.511.


Reference

1. Ji R, Koh MS, Irving LB. Cutaneous sarcoidosis. Ann Acad Med Singapore. 2007. 36:1044–1045.
2. Fernandez-Faith E, McDonnell J. Cutaneous sarcoidosis: differential diagnosis. Clin Dermatol. 2007. 25:276–287.
Article
3. Akhdari N, Skalli HD, Lakhdar H. Erythematous lesions on the scalp. Sarcoidosis. Arch Dermatol. 2004. 140:1003–1008.
4. Marchell RM, Judson MA. Chronic cutaneous lesions of sarcoidosis. Clin Dermatol. 2007. 25:295–302.
Article
5. Tchernev G. Cutaneous sarcoidosis: the "great imitator": etiopathogenesis, morphology, differential diagnosis, and clinical management. Am J Clin Dermatol. 2006. 7:375–382.
6. Sulavik SB, Spencer RP, Weed DA, Shapiro HR, Shiue ST, Castriotta RJ. Recognition of distinctive patterns of gallium-67 distribution in sarcoidosis. J Nucl Med. 1990. 31:1909–1914.
7. Tuchinda C, Wong HK. Etanercept for chronic progressive cutaneous sarcoidosis. J Drugs Dermatol. 2006. 5:538–540.
8. Doherty CB, Rosen T. Evidence-based therapy for cutaneous sarcoidosis. Drugs. 2008. 68:1361–1383.
Article
9. Grutters JC, van den Bosch JM. Corticosteroid treatment in sarcoidosis. Eur Respir J. 2006. 28:627–636.
Article
10. Alexis JB. Sarcoidosis presenting as cutaneous hypopigmentation with repeatedly negative skin biopsies. Int J Dermatol. 1994. 33:44–45.
Article
11. Yoon CH, Lee CW. Case 6. Erythrodermic form of cutaneous sarcoidosis. Clin Exp Dermatol. 2003. 28:575–576.
12. Kim DH, Park YM, Kang H, Cho SH, Choi SW, Byun DG, et al. Seven cases of cutaneous sarcoidosis. Korean J Dermatol. 2000. 38:1070–1074.
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