J Korean Ophthalmol Soc.  2014 May;55(5):702-710. 10.3341/jkos.2014.55.5.702.

The Change of Retinal Nerve Fiber Layer Thickness after Posterior Chamber Phakic Intraocular Lens Implantation

• Lee TH
• Park JW
• Jeong SH
• Park SW

• KMID: 2218091
• DOI: http://doi.org/10.3341/jkos.2014.55.5.702

Abstract

PURPOSE
In the present study we evaluated the changes of measured retinal nerve fiber layer (RNFL) thickness using optical coherence tomography (OCT) after phakic intraocular lens (implantable collamer lens, ICL) implantation and analyzed the factors correlated with the changes of measured RNFL thickness.
METHODS
Forty eyes of 40 patients (Group A: 20 patients using spectral domain OCT and Group B: 20 patients using time domain OCT) who underwent ICL implantation were included in this study. RNFL thickness was measured 1 week before surgery and 1 month postoperatively using OCT. The changes of measured RNFL thickness and the correlation between patients' data were analyzed.
RESULTS
The postoperative measured RNFL thickness of the average, inferior, temporal, and superior quadrants were increased compared to preoperative measured RNFL thickness in Group A. Group B had similar results in the average, inferior, and superior quadrants (p < 0.05). However, the postoperative changes of RNFL measurements were not correlated with the preoperative spherical equivalent, the degree of spherical equivalent change and diopters of implanted lens (p > 0.05).
CONCLUSIONS
The measured RNFL thickness after ICL implantation may increase compared to the preoperative value. Caution should be taken when interpreting the RNFL thickness values measured by OCT in patients with myopia who undergo ICL implantation.

Keyword

Optical coherence tomography; Phakic intraocular lens implantation; Retinal nerve fiber layer

MeSH Terms

Humans
Myopia
Nerve Fibers*
Phakic Intraocular Lenses*
Retinaldehyde*
Tomography, Optical Coherence
Retinaldehyde

Figure

• 

  Figure 1. Optical coherence tomography (OCT) findings, Spectralis OCT (A) and Stratus OCT (B). (A) Data of six sectors of retinal nerve fiber layer (RNFL) thickness, including temporal (T), temporal superior (TS), temporal inferior (TI), nasal (N), nasal superior (NS), nasal inferior (NI) and were used (black arrow). Average thickness of RNFL were calculated by mean value of these six sectors. Superior quadrant and inferior quadrant data were obtained from mean value of TS and nasal superior (NS), TI and NI, respectively. (B) Data from the four quadrants of RNFL thickness were obtained in this Stratus OCT result (asterix), and the average thickness of RNFL were obtained from the table (arrow head).

• 

  Figure 2. Correlation of preoperative retinal nerve fiber layer (RNFL) thickness with the amounts of RNFL thickness change in average and each quadrants in Spectralis optical coherence tomography (OCT) group (group A). There were statistically significant negative correlation in preoperative average, nasal, inferior and temporal quadrant RNFL thickness with amounts of average, nasal, inferior and temporal increase, respectively.

• 

  Figure 3. Correlation of preoperative retinal nerve fiber layer (RNFL) thickness with the amounts of RNFL thickness change in average and each quadrants in Stratus optical coherence tomography (OCT) group (group B). There were statistically significant negative correlation in RNFL thickness of preoperative average, nasal and superior quadrant thickness with amounts of average, nasal, superior increase, respectively, which were similar results compared with Spectralis OCT group (group A).

Reference

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