J Korean Ophthalmol Soc.  2013 Mar;54(3):432-436. 10.3341/jkos.2013.54.3.432.

Efficacy and Intraoperative Characteristics of DisCoVisc for Cataract Surgery

• Lim SA
• Oh TH
• Kim HS

• KMID: 2216762
• DOI: http://doi.org/10.3341/jkos.2013.54.3.432

Abstract

PURPOSE
To compare the efficacy and intraoperative characteristics of DisCoVisc with those of Hyal 2000 (sodium hyaluronate 1.0%) in cataract surgery.
METHODS
Cataract surgery was performed on 60 eyes in 49 patients who were diagnosed with moderate cataracts. 30 eyes were performed with DisCoVisc and a control group with 30 eyes using Hyal 2000 (sodium hyaluronate 1.0%). Phacodynamics was evaluated including ultrasound (US) time, mean US intensity, cumulative dissipated energy (CDE), and amount of used balanced salt solution. Corneal endothelium and corneal thickness were measured preoperatively and 1 day and 1 month and 2 months postoperatively.
RESULTS
There were no statistically significant differences in phacodynamic parameters in the two groups. The central corneal thickness change from preoperatively to postoperatively in the DisCoVisc group was +0.07 +/- 2.44 microm and Hyal 2000 group +0.84 +/- 2.93 microm (p = 0.032) at 2 months. Corneal endothelial cell loss (ECL)(%) at 2 months was 7.67 +/- 8.01% in DisCoVisc group and 13.23 +/- 15.5% in the Hyal 2000 group (p = 0.005).
CONCLUSIONS
There was signicant difference between DisCoVisc and Hyal 2000 in the changes of CCT, ECD (Endothelial cell density). (DisCoVisc is effective and provides advantages both cohesive OVDs and dispersive OVDs).

Keyword

DisCoVisc; Endothelial cell loss; OVD (ophthalmic viscosurgical device)

MeSH Terms

Cataract
Corneal Endothelial Cell Loss
Endothelium, Corneal
Eye
Humans

Figure

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  Figure 1. Change of preoperative and postpoerative central corneal thickness (μm). p = 0.032.

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  Figure 2 . Change of preoperative and postoperative corneal endothelial cell density (cells/mm2).

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  Figure 3. Endothelial cell loss between preoperation and follow up 1 m, 2 m. *Endothelial cell loss rate follow up 2 m (p = 0.005).

Reference

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