J Korean Ophthalmol Soc.  2014 Nov;55(11):1693-1697. 10.3341/jkos.2014.55.11.1693.

Result of Visual Evoked Potential, Electroretinography and Electrooculography in Normal Subjects Using MonPack 3 System

Affiliations
  • 1Department of Ophthalmology, Konyang University College of Medicine, Daejeon, Korea. jin-sy@hanmail.net

Abstract

PURPOSE
We present the results of visual evoked potential (VEP), electroretinography (ERG), and electrooculography (EOG) in normal subjects using the Mon-pack 3 system (Metrovision).
METHODS
VEP, ERG, and EOG were obtained in 92 normal eyes. The measurements followed the International Society for Clinical Electrophysiology of Vision (ISCEV) standardization protocol. In VEP, the standard electrode was placed on the forehead and the active electrode was attached on the occiput. In ERG, a 20-minute dark adaptation was performed after mydriasis, and an ERG-jet electrode was used. EOG was measured by attaching an electrode to each medial canthal skin. Each latent period and electric potential was measured with average, standard deviation, median, and 95% confidencenterval (95% CI).
RESULTS
The mean P100 latency in pattern VEP was 104.36 ms, and P100 latency in flash VEP was 116.71 ms. For the maximal ERG response, the implicit times of a and b waves were 22.65 ms and 44.58 ms, respectively and the amplitude of a and b waves were 274.09 microv and 489.52 microv, respectively. For the ERG cone response, the implicit time of a and b waves were 18.21 ms and 33.40 ms, respectively, and the amplitude of a and b waves were 35.87 microv and 104.42 microv, respectively. The mean ERG oscillitatory potential was 285.53 microv. The average EOG Arden ratio was 2.54.
CONCLUSIONS
VEP, ERG, and EOG results from normal subjects using the Mon-pack 3 system can be applied to the diagnosis of retina and optic nerve disease and basic research.

Keyword

Electrooculography; Electroretinography; Mon-pack 3 system (Metrovision); Normal subjects; Visual evoked potential

MeSH Terms

Dark Adaptation
Diagnosis
Electrodes
Electrooculography*
Electrophysiology
Electroretinography*
Evoked Potentials, Visual*
Forehead
Mydriasis
Optic Nerve Diseases
Retina
Skin

Reference

References

1. Ganes T. Somatosensory evoked responses and central afferent conduction times in patients with multiple sclerosis. J Neurol Neurosurg Psychiatry. 1980; 43:948–53.
Article
2. Choi SH, Ohn YH. VER changes in refractive error. J Korean Ophthalmol Soc. 1999; 40:2876–83.
3. Sokol S. Pattern visual evoked potentials: their use in pediatric ophthalmology. Int Ophthalmol Clin. 1980; 20:251–68.
4. DeVoe RC, Ripps H, Vaughan HG Jr. Cortical responses to stimulation of the human fovea. Vision Res. 1968; 8:135–47.
Article
5. Oken BS, Chiappa KH, Gill E. Normal temporal variability of the P100. Electroencephalogr Clin Neurophysiol. 1987; 68:153–6.
Article
6. Halliday AM, McDonald WI, Mushin J. Visual evoked response in diagnosis of multiple sclerosis. Br Med J. 1973; 4:661–4.
Article
7. Sokol S. Abnormal evoked potential latencies in amblyopia. Br J Ophthalmol. 1983; 67:310–4.
Article
8. Asselman P, Chadwick DW, Marsden DC. Visual evoked responses in the diagnosis and management of patients suspected of multiple sclerosis. Brain. 1975; 98:261–82.
Article
9. Kupersmith MJ, Weiss PA, Carr RE. The visual-evoked potential in tobacco-alcohol and nutritional amblyopia. Am J Ophthalmol. 1983; 95:307–14.
Article
10. Sim JO, Park CK, Moon JI. Clinical ability of high frequency pattern VEP and flicker ERG examination to detect glaucomatous visual field change. J Korean Ophthalmol Soc. 2004; 45:1315–21.
11. Yoo WS, Park YJ, Yoo JM. Pattern VEP in adult amblyopic patients requested from military service. J Korean Ophthalmol Soc. 2010; 51:1392–7.
Article
12. Chang BL. VEP in normal eyes. J Korean Ophthalmol Soc. 1987; 28:127–30.
13. Kim SM, Kwak HW, Oh YD. Evaluation of clinically applied VEP (visual evoked potential) in ophthalmological and neurological diseases. J Korean Ophthalmol Soc. 1985; 26:1041–5.
14. Shin HH, Park SH, Im MJ. The latency time of visual evoked potential in normal eyes. J Korean Ophthalmol Soc. 1986; 27:205–10.
15. Choi SH, Ohn YH, Shin HH. Normal value of standard electroretinography and change with age and sex (II)-results using Burian-Allen electrode and comparison with results using EFG-jet electrode. J Korean Ophthalmol Soc. 1999; 40:129–40.
16. Arden GB, Barrada A. Analysis of the electro-oculograms of a series of normal subjects: role of the lens in the development of the standing potential. Br J Ophthalmol. 1962; 46:468–82.
Article
17. Fishman GA, Carrasco C, Fishman M. The electro-oculogram in diffuse (familial) drusen. Arch Ophthalmol. 1976; 94:231–3.
Article
18. Kolb H. Electro-oculogram findings in patients treated with anti-malarial drugs. Br J Ophthalmol. 1965; 49:573–90.
Article
19. van Lith GH, Balik J. Variability of the electro-oculogram (EOG). Acta Ophthalmol (Copenh). 1970; 48:1091–6.
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