J Korean Ophthalmol Soc.  2014 Nov;55(11):1600-1605. 10.3341/jkos.2014.55.11.1600.

Objective Optical Quality Analysis in Dry Eye Syndrome

• Jeon HM
• Lee DJ

• KMID: 2216606
• DOI: http://doi.org/10.3341/jkos.2014.55.11.1600

Abstract

PURPOSE
To evaluate the efficacy of Optical Quality Analysis System (OQAS(R)) instrument for the assessment of dry eye syndrome.
METHODS
Dynamic recording of double-pass (DP) retinal images was performed in 1 eye dry eye patients (20 eyes) and in healthy controls (20 eyes) for 20 seconds after eye blinking.
RESULTS
The mean objective scatter Index (OSI) value was 4.53 in dry eyes, 0.67 in healthy eyes and the standard deviation of OSI was 1.20 in dry eyes and 1.18 in healthy eyes. The patients with dry eyes showed significantly higher mean OSI and standard deviation values. Ocular scatter increased over time and significant changes occurred 13.5 seconds after blinking. The difference in OSI value between 0 second and 20 seconds was significantly greater in dry eye patients (4.15) than in controls (0.32).
CONCLUSIONS
Ocular scatter increased over time after blinking. The dry eye patients had larger and more variable ocular scatter index than the controls. OQAS(R) may be useful to detect and follow-up tear film-related patient complaints in dry eye syndrome.

Keyword

Dry eye syndrome; Ocular scattering; OQAS(R); OSI

MeSH Terms

Blinking
Dry Eye Syndromes*
Humans
Retinaldehyde
Tears
Retinaldehyde

Figure

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  Figure 1. Mean objective scatter index (OSI) value obtained from double-pass image series of all eyes in control group (A) and dry eye group (B).

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  Figure 2. Continuous measured objective scatter index (OSI) in control group (A) and in dry eye group (B). OSI is larger and more variable in dry eye patients.

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  Figure 3. Standard deviation of objective scatter index (OSI) value obtained from double-pass image series of all eyes in control group (A) and dry eye group (B).

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  Figure 4. Result papers from continuous recording of double pass retinal image. (A) Normal control patient without dry eye symptoms. (B) Mild dry eye syndrome (DES) patient. (C) Severe DES patient with filamentary keratitis. OSI = objective scatter index.

Reference

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