J Korean Ophthalmol Soc.  2010 Nov;51(11):1485-1490. 10.3341/jkos.2010.51.11.1485.

Relationship Between Central Corneal Thickness and Scleral Thickness in Korean Glaucomatous Patients

• Ha SG
• Kim YY

• KMID: 2213976
• DOI: http://doi.org/10.3341/jkos.2010.51.11.1485

Abstract

PURPOSE
To evaluate the correlation between central corneal thickness (CCT) and scleral thickness (ST) in glaucoma patients.
METHODS
Seventy-eight eyes of 78 patients with no previous history of intraocular surgery and 23 control eyes were enrolled in the present study. For all eyes, CCT, ST, axial length, anterior chamber depth and refractive error were measured by a single examiner. The correlations among the measurements were analyzed.
RESULTS
The mean patient age was 57.32 +/- 9.44 years, and the mean CCT was 532.80 +/- 43.75 microm. The mean CCT of ocular hypertension (576.00 +/- 26.59 microm) was thicker than that of the normal control group (530.30 +/- 35.34 microm, p = 0.028), although the mean STs of the groups were not significantly different. No significant correlation was found between CCT and ST (r = -0.073, p = 0.466).
CONCLUSIONS
In the present study, no correlation between CCT and ST was observed. In addition, the STs of the groups were not significantly different.

Keyword

Central corneal thickness; Scleral thickness; Ultrasound biomicroscopy

MeSH Terms

Anterior Chamber
Eye
Glaucoma
Humans
Microscopy, Acoustic
Ocular Hypertension
Refractive Errors

Figure

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  Figure 1. Ultrasound biomicroscopic image of the temporal corneoscleral limbus demonstrates the limits of episcleral tis-sue-sclera (outer yellow arrows) and sclera-ciliary body inter-faces (inner red arrows) at the three sites of measurements, the scleral spur (ST1), 2.0 and 3.0 mm posterior to it (ST2 and ST3, respectively).

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  Figure 2. Anterior chamber depth (ACD) (Fig. A, B) and central corneal thickness (CCT) (Fig. C, D) in total patients. ACD in chronic angle closure glaucoma group was significantly narrower than control and that of the primary open angle glaucoma groups (p = 0.01, 0.00). CCT in ocular hypertension group was significantly thicker than control group and CCT in normal tension glaucoma group was significantly thiner than that of the control group (p = 0.00, 0.02). POAG = priamry open angle glaucoma; CACG = chronic angle closure glaucoma; NTG = normal tension glaucoma; OHT = ocular hypertension; Nor = normal controls.

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  Figure 3. Correlation between central corneal thickness and scleral thickness (ST1) in total patinets. There was no correlation between central corneal thickness and scleral thickness (r =-0.073, p = 0.620).

Reference

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