J Korean Ophthalmol Soc.  2009 Oct;50(10):1582-1585. 10.3341/jkos.2009.50.10.1582.

A Case of Primary Mucinous Adenocarcinoma on Skin of The Lateral Canthus

• Hong SM
• Kim SD
• Yun KJ

• KMID: 2212779
• DOI: http://doi.org/10.3341/jkos.2009.50.10.1582

Abstract

PURPOSE
To report a rare case of primary mucinous adenocarcinoma arising from a sweat gland in the eyelid.
CASE SUMMARY
A 68-year-old male presented to our hospital with a painless, superficial nodular lesion over the skin of the right lateral canthus that had slowly grown over the past two years. The patient had a history of surgical excision for three nodular lesions at the same site 5 years ago, and an excisional biopsy was mucinous adenocarcinoma with a positive margin. A systemic evaluation, including whole-body Positron Emission Tomography scan (PET), chest computerized tomography, gastrointestinal endoscopy, and colonoscopy, revealed no other abnormal lesions. Therefore, the eyelid lesion was considered a primary mucinous adenocarcinoma of the skin.
CONCLUSIONS
Primary mucinous adenocarcinoma of the eyelid can rarely metastasize. Therefore, a systemic examination is warranted to discriminate primary and metastatic adenocarcinoma and also to monitor the long-term follow-up for the evaluation of local recurrence.

Keyword

Lateral Canthus; Primary mucinous adenocarcinoma; Sweat gland

MeSH Terms

Adenocarcinoma
Adenocarcinoma, Mucinous
Aged
Biopsy
Colonoscopy
Endoscopy, Gastrointestinal
Eyelids
Humans
Male
Mucins
Organothiophosphorus Compounds
Positron-Emission Tomography
Recurrence
Skin
Sweat Glands
Thorax
Mucins
Organothiophosphorus Compounds

Figure

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  Figure 1. Recurrent nodular mass on the right lateral canthus, 5 years after initial surgical resection of mucinous adenocarcinoma in the same location.

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  Figure 2. The tumor was divided into numerous compart-ments. In each compartment, large mucin pools contain the tumor cells (H&E, ×100).

Reference

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