J Korean Surg Soc.  2011 Jun;80(6):384-389. 10.4174/jkss.2011.80.6.384.

Risk factors for postoperative ileus after urologic laparoscopic surgery

Affiliations
  • 1Department of Urology, Kyung Hee University School of Medicine, Seoul, Korea. juro@khu.ac.kr

Abstract

PURPOSE
Although its incidence has decreased with the widespread use of less invasive surgical techniques including laparoscopic surgery, postoperative ileus remains a common postoperative complication. In the field of urologic surgery, with the major exception of radical cystectomy, few studies have focused on postoperative ileus as a complication of laparoscopic surgery. The present study aims to offer further clues in the management of postoperative ileus following urological laparoscopic surgery through an assessment of the associated risk factors.
METHODS
The medical records of 267 patients who underwent laparoscopic surgery between February 2004 and November 2009 were reviewed. After excluding cases involving radical cystectomy, combined surgery, open conversion, and severe complications, a total of 249 patients were included for this study. The subjects were divided into a non-ileus group and an ileus group. The gender and age distribution, duration of anesthesia, American Society of Anesthesiologists Physical Status Classification Score, body mass index, degree of operative difficulty, presence of complications, surgical procedure and total opiate dosage were compared between the two groups.
RESULTS
Of the 249 patients, 10.8% (n = 27) experienced postoperative ileus. Patients with ileus had a longer duration of anesthesia (P = 0.019), and perioperative complications and blood loss were all correlated with ileus (P = 0.000, 0.004, respectively). Multiple linear regression analysis showed that the modified Clavien classification was an independent risk factor for postoperative ileus (odds ratio, 5.372; 95% confidence interval, 2.084 to 13.845; P = 0.001).
CONCLUSION
Postoperative ileus after laparoscopic urologic surgery was more frequent in patients who experienced more perioperative complications.

Keyword

Urology; Laparoscopy; Complication; Ileus

MeSH Terms

Age Distribution
Anesthesia
Body Mass Index
Cystectomy
Humans
Ileus
Incidence
Laparoscopy
Linear Models
Medical Records
Postoperative Complications
Risk Factors
Urology

Reference

1. Delaney C, Kehlet H, Senagore AJ, Bauer AJ, Beart R, Billingham R, editors. Clinical consensus update in general surgery [Internet]. 2006. cited 2008 May 1. Roswell: Pharmatecture, LLC;Available from: http://www.clinicalwebcasts.com/pdfs/GenSurg_WEB.pdf.
2. Iyer S, Saunders W. Impact of post-operative ileus (POI) on hospital length of stay in colectomy surgery patients [abstract]. In : American College of Gastroenterology Annual Scientific Meeting; 2007 Oct 12-17; Philadelpia, PA.
3. Holte K, Kehlet H. Postoperative ileus: a preventable event. Br J Surg. 2000. 87:1480–1493.
4. Artinyan A, Nunoo-Mensah JW, Balasubramaniam S, Gauderman J, Essani R, Gonzalez-Ruiz C, et al. Prolonged postoperative ileus-definition, risk factors, and predictors after surgery. World J Surg. 2008. 32:1495–1500.
5. Livingston EH, Passaro EP Jr. Postoperative ileus. Dig Dis Sci. 1990. 35:121–132.
6. Story SK, Chamberlain RS. A comprehensive review of evidence-based strategies to prevent and treat postoperative ileus. Dig Surg. 2009. 26:265–275.
7. Chang SS, Cookson MS, Baumgartner RG, Wells N, Smith JA Jr. Analysis of early complications after radical cystectomy: results of a collaborative care pathway. J Urol. 2002. 167:2012–2016.
8. Chang SS, Baumgartner RG, Wells N, Cookson MS, Smith JA Jr. Causes of increased hospital stay after radical cystectomy in a clinical pathway setting. J Urol. 2002. 167:208–211.
9. Gamé X, Soulié M, Seguin P, Vazzoler N, Tollon C, Pontonnier F, et al. Radical cystectomy in patients older than 75 years: assessment of morbidity and mortality. Eur Urol. 2001. 39:525–529.
10. Guillonneau B, Abbou CC, Doublet JD, Gaston R, Janetschek G, Mandressi A, et al. Proposal for a "European Scoring System for Laparoscopic Operations in Urology". Eur Urol. 2001. 40:2–6.
11. Eipe N, Ponniah M. Perioperative blood loss assessment: how accurate? Indian J Anaesth. 2006. 50:35–38.
12. Wolters U, Wolf T, Stützer H, Schröder T. ASA classification and perioperative variables as predictors of postoperative outcome. Br J Anaesth. 1996. 77:217–222.
13. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004. 240:205–213.
14. Behm B, Stollman N. Postoperative ileus: etiologies and interventions. Clin Gastroenterol Hepatol. 2003. 1:71–80.
15. Ferraz AA, Cowles VE, Condon RE, Carilli S, Ezberci F, Frantzides CT, et al. Nonopioid analgesics shorten the duration of postoperative ileus. Am Surg. 1995. 61:1079–1083.
16. Lacy AM, García-Valdecasas JC, Piqué JM, Delgado S, Campo E, Bordas JM, et al. Short-term outcome analysis of a randomized study comparing laparoscopic vs open colectomy for colon cancer. Surg Endosc. 1995. 9:1101–1105.
17. Schwenk W, Böhm B, Haase O, Junghans T, Müller JM. Laparoscopic versus conventional colorectal resection: a prospective randomised study of postoperative ileus and early postoperative feeding. Langenbecks Arch Surg. 1998. 383:49–55.
18. Milsom JW, Böhm B, Hammerhofer KA, Fazio V, Steiger E, Elson P. A prospective, randomized trial comparing laparoscopic versus conventional techniques in colorectal cancer surgery: a preliminary report. J Am Coll Surg. 1998. 187:46–54.
19. Leung KL, Lai PB, Ho RL, Meng WC, Yiu RY, Lee JF, et al. Systemic cytokine response after laparoscopic-assisted resection of rectosigmoid carcinoma: a prospective randomized trial. Ann Surg. 2000. 231:506–511.
20. Bauer AJ, Boeckxstaens GE. Mechanisms of postoperative ileus. Neurogastroenterol Motil. 2004. 16:Suppl 2. 54–60.
21. Person B, Wexner SD. The management of postoperative ileus. Curr Probl Surg. 2006. 43:6–65.
22. Hollenbeck BK, Miller DC, Taub D, Dunn RL, Khuri SF, Henderson WG, et al. Identifying risk factors for potentially avoidable complications following radical cystectomy. J Urol. 2005. 174(4 Pt 1):1231–1237.
Full Text Links
  • JKSS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr