J Pathol Transl Med.  2016 Mar;50(2):165-167. 10.4132/jptm.2015.07.15.

A Rare Case of Thymic Gangliocytic Paraganglioma

• Yang JW
• Han J
• Lee HW
• Cho SY
• Kim HK

• KMID: 2211385
• DOI: http://doi.org/10.4132/jptm.2015.07.15

Abstract

No abstract available.

MeSH Terms

Paraganglioma*

Figure

• 

  Fig. 1. Thymic gangliocytic paraganglioma. (A) Chest computed tomography reveals a well-circumscribed ovoid mass (white arrow) in the anterior mediastinum. (B) On low-power view, the mass shows an expanding border surrounded by normal thymic tissue. (C) Spindle cells show an intersecting fascicular pattern, and fibrillary cells show a vague or confluent nesting pattern (black arrow). Scattered ganglion-like cells (white thick arrow) and epithelioid cells (black thick arrow) are also noted. (D) Epithelioid cells form a vague nesting pattern. (E) Epithelial cells show a branching pattern (arrowhead) between the nests of fibrillary cells (black arrow). (F) In focal areas, the epithelial cells form compressed cords and ducts (left upper corner). (G, H) Staining with CD56 (G) and synaptophysin (H) is positive for spindle cells, ganglion-like cells, epithelioid cells, and fibrillary cells. (I) Only spindle cells are positive for S-100. Spindle cells are located adjacent to and within the nests of fibrillary cells. (J) On staining for AE1/AE3, the epithelial cells show a reticular or race-like cytoplasmic pattern. (K, L) Some of the fibrillary cells and epithelioid cells are positive (K) for progesterone receptor, but most of them are negative (L).

Reference

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