J Korean Ophthalmol Soc.  2008 Jan;49(1):111-118. 10.3341/jkos.2008.49.1.111.

The Effect of Internal Limiting Membrane Peeling on Retinal Vein Occlusion Induced Macular Edema

• Seo WM
• Kim IT

• KMID: 2211190
• DOI: http://doi.org/10.3341/jkos.2008.49.1.111

Abstract

PURPOSE: To evaluate the effect of pars plana vitrectomy with indocyanine green-assisted peeling of the internal limiting membrane (ILM) on visual acuity in macular edema in RVO patients.
METHODS
Twenty-three eyes of 23 patients were treated consecutively (male: female=7:16). Thirteen patients were BRVO, and ten patients were CRVO. Vitrectomy that involved peeling the ILM with the assistance of indocyanine dye was performed in all 23 eyes. A visual acuity change of 2 lines or more was regarded as significant. We compared preoperative BCVA and postoperative BCVA.
RESULTS
Improvement of visual acuity was observed in 13 eyes (8 eyes in BRVO, 5 eyes in CRVO) of 23 total eyes (56.5%). No change in visual acuity was observed in 5 eyes (3 eyes in BRVO, 2 eyes in CRVO). Worsening of visual acuity was observed in 5 eyes (2 eyes in BRVO, 3 eyes in CRVO).
CONCLUSIONS
Pars plana vitrectomy with ILM peeling in patients with macular edema induced by RVO showed visual improvement in 56.5% of the cases in our study (61.5% in BRVO, 50% in CRVO). PPV with ILM peeling may be an effective procedure in reducing macular edema due to RVO.

Keyword

Internal limiting membrane; Macular edema; Retinal vein occlusion

MeSH Terms

Eye
Humans
Macular Edema
Membranes
Retinal Vein
Retinal Vein Occlusion
Retinaldehyde
Visual Acuity
Vitrectomy
Retinaldehyde

Figure

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  Figure 1. Scatterplot illustrating visual acuity before and after ILM peeling in BRVO.

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  Figure 2. Scatterplot illustrating visual acuity before and after ILM peeling in CRVO.

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  Figure 3. Preoperative (A, B, C) and postoperative (D, E, F) fundus, fluorescein angiography and OCT appearance in case 13 with BRVO show reduced intraretinal hemorrhage (D), intraretinal leaking and stain (E), and macular thickness (F).

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  Figure 4. Preoperative (A, B, C) and postoperative (D, E, F) fundus, fluorescein angiography and OCT appearance in case 2 with CRVO show reduced intraretinal hemorrhage (D), intraretinal leaking and stain (E), and macular thickness (F).

Reference

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