J Korean Surg Soc.  2000 Jan;58(1):127-131.

Metastatic Gastrointestinal Autonomic Nerve Tumor in Liver

• Park WC
• So BJ
• Chae KM
• Yoon KH
• Yun KJ

Abstract

Gastrointestinal autonomic nerve tumors (GANT) are uncommon neoplasms of the gastrointestinal tract. The GANT is a specialized form of stromal neoplasm with the feature of myenteric plexus derivation. We report a patient with a GANT of the small intestine and liver metastasis. The patient was admitted for evaluation of hematochezia and a palpable abdominal mass. A CT of the abdomen showed an exophytic mass arising from the distal ileum and exhibiting deep ulceration and air-cavity formation, and a huge cystic mass in the right lobe of the liver. The gross appearance of a surgical specimen of the liver showed a huge cystic mass, containing liquified hemorrhagic fluid, with an irregular nodular peripheral portion. Its capsule was intact. An ileal mass, measuring 9x5 cm and arising from the submucosal layer, with deep ulceration was seen. Histological examination of the liver and the ileal mass revealed a malignant stromal tumor with neural differentiation on immunohistochemical staining.

Keyword

Gastrointestinal autonomic nerve tumor; Ileum; Liver

MeSH Terms

Abdomen
Autonomic Pathways*
Gastrointestinal Hemorrhage
Gastrointestinal Tract
Humans
Ileum
Intestine, Small
Liver*
Myenteric Plexus
Neoplasm Metastasis
Ulcer