J Korean Radiol Soc.  2004 Dec;51(6):599-607. 10.3348/jkrs.2004.51.6.599.

Experimental Study for Comparison of the Ablation Effects of Extracted Bovid Liver by Percutaneous Procedures with Ethanol, Microwave, and Radiofrequency

• Kang BJ
• Hahn ST

• KMID: 2209164
• DOI: http://doi.org/10.3348/jkrs.2004.51.6.599

Abstract

PURPOSE: The purpose of this study was to evaluate the differences in the ablation effects of percutaneous ethanol injection therapy (PEIT), percutaneous microwave coagulation therapy (PMCT), and radiofrequency (RF) ablation therapy in extracted bovid livers, and to assess the appropriate therapeutic method for treating hepatic tumors according to their shape, size and location.
MATERIALS AND METHODS
PEIT, PMCT and RF ablation were performed at 1 cm and 5 cm depth in bovid livers. PEIT was performed with 1, 2, 3 and 4 ml of ethanol, PMCT with 60 watt for a 30 th, 60 th and 120 th of a second, and RF ablation for 6, 8, 10, 12 and 14 minutes. Ultrasonography was used for the detection of the tissue necrosis that followed the different therapeutic modalities.
RESULTS
For PEIT, the extent of the necrosis was smaller than that of the other modalities. For PMCT, the necrosis was elliptical and longer in length. For RF, the necrosis was oval and larger in size. At 1 cm depth for PMCT and RF ablation, the liver capsule was injured.
CONCLUSION
We concluded that these different findings in tissue necrosis would aid in selecting the appropriate therapeutic method for hepatic tumors according to the tumors' shape, size and location.

Keyword

Liver, neoplasms; Ethanol; Microwaves; Ultrasound (US)

MeSH Terms

Ethanol*
Liver*
Microwaves*
Necrosis
Ultrasonography
Ethanol