J Korean Pediatr Soc.  1994 Mar;37(3):410-415.

A Case of Rotor Syndrome

Abstract

We experienced a case of Rotor syndrome in an 8 year 6 month old boy who presented with icteric sclera and icteric skin on whole body. His clinical and laboratory characteristics were as follows; 1) Jaundice appeared from several months ago before admission without any clinical disturbance. 2) Direct bilirubin was more increased than indirect bilirubin. 3) Plasma indocyanine green (ICG) kinetics test revealed hepatic excretory in this patient that after intravenous injection of a standard dose of ICG (0.5mg/kg), its initial plasma disappearance is decreased, resultin in markedly increased retention of the dye 45 to 50 minutes after administration. 4) Oral cholangiography, ultrasonogram, and computed tomogram of abdomen were normal. 5) Liver biopsy specimen showed no dark brown pigmentations in the hepatic cells and any other pathologic abnormalities. 6) Nearly similar clinical and laboratory findings were observed 26 months later.


MeSH Terms

Abdomen
Bilirubin
Biopsy
Cholangiography
Hepatocytes
Humans
Hyperbilirubinemia, Hereditary*
Indocyanine Green
Infant
Injections, Intravenous
Jaundice
Kinetics
Liver
Male
Pigmentation
Plasma
Sclera
Skin
Ultrasonography
Bilirubin
Indocyanine Green
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