J Korean Ophthalmol Soc.
2005 Feb;46(2):279-286.
Diurnal Variation of Macular Thickness in Diabetic Macular Edema
- Affiliations
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- 1Department of Ophthalmology, Korea University College of Medicine, Seoul, Korea. dumky@unitel.co.kr
Abstract
- PURPOSE
To evaluate the diurnal variation of macular thickness in eyes with diabetic macular edema. METHODS: We measured macular thickness using optical coherence tomography in 33 eyes with diabetic macular edema and 33 normal control eyes at 7 am, 11 am, 2 pm, and 5 pm. We investigated the correlation between macular thickness change and several factors such as sex, duration of diabetes mellitus, presence of hypertension, HbA1c, creatinine clearance, blood urea nitrogen, serum creatinine, blood sugar, blood pressure, severity of diabetic retinopathy, and whether PRP was done or not. RESULTS: Retinal thickness in 3.45 mm macular area was the thickest at 7 am and then decreased over the day to be thinnest at 5 pm (p
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