J Korean Pediatr Soc.  2000 Jun;43(6):832-836.

A Case of Candida Endocarditis with Vegetation on the Tricuspid Valve in a Preterm Infnat

• Han HY
• Jung MJ
• Lee KH
• Kim GH
• Lee HS
• Park GY
• Oh YH

Abstract

Fungal endocarditis is a rare disease in infants, but it has been reported with increasing frequency among premature infants requiring neonatal intensive care. Congenital heart disease, pro- longed intravenous catheterization, the use of intravenous alimentation, broad-spectrum antibiotics administration and narcotic addiction are risk factors. Candida endocarditis is an unusual but severe complication of systemic candidiasis. Its occurrence has been related to the placement of a central venous catheter with its tip close to or within the right atrium and persistent candidemia. Embolization to major blood vessels is a common complication of Candida endocarditis and repeated pulmonary emboli are suspected to be cause of the repeated episodes of circulatory shock which finally leads to death. Thus, early diagnosis of Candida invasion and prevention of Candida endocarditis are essential for survival. We report a case of Candida endocarditis which was successfully managed with surgical removal and antifungal therapy. (J Korean Pediatr Soc 2000;43:832 836)

Keyword

Candida endocarditis; Vegetation; Tricuspid valve

MeSH Terms

Anti-Bacterial Agents
Blood Vessels
Candida*
Candidemia
Candidiasis
Catheterization
Catheters
Central Venous Catheters
Early Diagnosis
Endocarditis*
Heart Atria
Heart Defects, Congenital
Humans
Infant
Infant, Newborn
Infant, Premature
Intensive Care, Neonatal
Opioid-Related Disorders
Rare Diseases
Risk Factors
Shock
Tricuspid Valve*
Anti-Bacterial Agents