J Korean Ophthalmol Soc.  2004 Jan;45(1):152-159.

FAG, ICG and OCT Findings in Multiple Evanescent White Dot Syndrome

• Lee HS
• Byun YJ
• Kang SM

Abstract

PURPOSE
We evaluated one patient with multiple evanescent white dot syndrome (MEWDS), using fundus fluorescein angiography (FAG), indocyanine green angiography (ICGA), optical coherence tomography (OCT) on acute phase of the disease, at 2 weeks after onset and at 10weeks. METHODS: Each diagnostic images were compared with patient's clinical course .OCT measurements of serial retinal thickness were done to assess the change in retinal thickness over the disease process. RESULTS: White dots on fundoscopic examination showed hypofluorescent on ICGA and imaged hyperreflective on OCT without presence of neither subretinal fluid nor neuroretinal increase in thickness. These ICGA and OCT findings suggest that lesions of perfusion defect on ICGA may be caused by interstitial precipitations of inflammatory cells in choriocapillaries and the underlying mechanism is not due to vasculitis with edema or serous exudation. CONCLUSIONS: ICGA and OCT allowed more precise anatomic evaluation than FAG in diagnosis and correlated well with clinical symptoms.

Keyword

Choriocapillary inflammation; ICGA, MEWDS; OCT

MeSH Terms

Angiography
Diagnosis
Edema
Fluorescein Angiography
Humans
Indocyanine Green
Perfusion
Retinaldehyde
Subretinal Fluid
Tomography, Optical Coherence
Vasculitis
Indocyanine Green
Retinaldehyde