J Korean Ophthalmol Soc.  2004 Jan;45(1):141-145.

A Case of Ocular Hydroxyapatite Infection Diagnosed by Technetium 99m-labeled Leukocyte Scintigraphy

• Lee JH
• Lew YJ
• Moon SH
• Jang JW
• Lew HM

Abstract

PURPOSE
To describe a low-grade infection of hydroxyapatite orbital implant diagnosed by 99mTc-labeled leukocyte scintigraphy. METHODS: A 34-year-old man diagnosed as phthisis bulbi due to corneoscleral laceration on left eye had been treated with evisceration and hydroxyapatite orbital implant insertion. After drilling for ocular prosthesis, the patient did not have any symptom for 3 years and 5 months. He presented with socket pain, erythematous lid swelling, severe conjunctival discharge. There was no improvement of symptom despite conservative treatment for 3 weeks. MRI revealed no abnormalities so 99mTc-labeled leukocyte scintigraphy was performed. RESULTS: Scintigraphy showed a dense accumulation of labeled leukocyte at the implant site. After diagnosed as hydroxyapatite orbital implant infection, orbital implant was removed and silicon sphere implantation was done. After operation, the inflammation signs disappeared. CONCLUSIONS: 99mTc-labeled leukocyte scintigraphy is a useful technique in diagnosing low-grade infection of hydroxyapatite orbital implant undetected using conventional imaging method such as MRI.

Keyword

Hydroxyapatite infection; Leukocyte scintigraphy

MeSH Terms

Adult
Durapatite*
Eye, Artificial
Humans
Inflammation
Lacerations
Leukocytes*
Magnetic Resonance Imaging
Orbital Implants
Radionuclide Imaging*
Silicones
Technetium*
Durapatite
Silicones
Technetium