J Korean Ophthalmol Soc.  2003 Aug;44(8):1948-1953.

A Case of Vitreous Amyloidosis

Affiliations
  • 1Department of Ophthalmology, Ilsan Paik Hospital Inje University College of Medicine, Korea. phb@ilsanpaik.ac.kr
  • 2Department of Ophthalmology, Sanggye Paik Hospital Inje University College of Medicine, Korea.

Abstract

PURPOSE
To report a case of vitreous amyloidosis. METHODS: A 51-year old male presented with bilateral floater and decreased visual acuity of 3 months duration. Small white dots attached to the posterior lens surface were observed on slit lamp examination. The vitreous opacity, which connected with the small white dots to the posterior lens surface, were observed on funduscopic examination, and multiple hyperechoic plaques in the vitreous cavity on B-scan. The pars plana vitrectomy was performed. RESULTS: The aspirate of the pars plana vitrectomy was stained with Congo red and observed with light microscope, and polarized light. Electron microscopy was also performed. The vitreous smear stained with Congo red showed greenish dichroism and birefringent nature with polarized light and fine fibrillar nature of amyloid material was noted on electron microscopy. CONCLUSIONS: To our knowledge, this is the first Korean report of vitreous amyloidosis. The authors diagnosed vitreous amyloidosis that developed in a 51-year-old male patient. The diagnosis was confirmed by light microscope, polarized light and electron microscope.

Keyword

Amyloidosis; Birefringence; Congo red; Dichroism

MeSH Terms

Amyloid
Amyloidosis*
Birefringence
Congo Red
Diagnosis
Humans
Male
Microscopy, Electron
Middle Aged
Visual Acuity
Vitrectomy
Amyloid
Congo Red
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