J Korean Ophthalmol Soc.
1988 Jun;29(3):283-288.
Ultrastructure of Langerhans Cell and Expression of HLA-DR Antigen in Normal Limbal Conjunctiva
- Affiliations
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- 1Department of Ophthalmology, School of Medicine, Hanyang University, Seoul, Korea.
Abstract
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We have observed the ultrastructures of Langerhans cell in the normal limbal eonjunctiva by electron microscopy and expression of HLA-DR antigen by peroxidase-antiperoxidase(PAP) method in the normal limbal conjunctiva. In electron microscope, Langerhans cell had no junctional complex like desmosome, irregular and invaginated nucleus, and characteristic Birbeck granlues in the cytoplasm. In PAP method, HLA-DR-positive cells were found in basal or suprabasal layer of conjunctival epithelium as dendritic form.