J Korean Ophthalmol Soc.  1988 Apr;29(2):453-457.

A Case of Solitary Metastatic Iris Tumor from Bronchogenic Carcinoma: Responese to Chemotherapy

• Kim SJ
• Shim CB
• Oh JS
• Jeon YJ

Abstract

Metastatic tumors to the eye are probably the most common type of intraocular malignancies. The choroid is the most common site of involvement. Though the iris is a less common site of uveal involvement, metastases to the iris may occur and may produce a variety of clinical findings. The most common metastatic tumor to the eye is breast tumor and lung tumor is second, whereas the prompt most common metastatic tumor to the iris is lung tumor and breast tumor is second. The iris lesion may be the first presentation of the cancer and should make a search for the primary tumor. The diagnosis of metastatic tumor to the iris can be established by cytologic examination of aqueous. Local irradiation can spare the patient an enucleation and can preserve the eye for the generally few months of life that remain. Although the prognosis for vision is usually good, the prognosis for life is poor. The authors describe a 37 year old male patient having a metastasis from oat cell carcinoma of the lung to iris, which begins to respond to chemotherapy.

MeSH Terms

Adult
Breast Neoplasms
Carcinoma, Bronchogenic*
Carcinoma, Small Cell
Choroid
Diagnosis
Drug Therapy*
Humans
Iris*
Lung
Male
Neoplasm Metastasis
Prognosis