J Korean Ophthalmol Soc.
1988 Apr;29(2):309-314.
The Standardization of Visual Evoked Potential in Pigmented Rabbits
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- 1Department of Ophthalmology, Kyungpook National University, Taegu, Korea.
Abstract
- VEP is an objective method for the evaluation of macular function and optic nerve disease, but its large inter and intraindividual variation prevented clinical and experimental application. We recorded a relatively stable VEP A wave in pigmented rabbits with cortical electrode and following results were obtained. The amplitude of VEP A wave was 97.8 +/- 29.8 micro V and latent time was 52.2 +/- 6.9 msec. Inter- and intraindividual variation of VEP latent time was much smaller than that of VEP amplitude. So latent time of VEP A wave may be a good indicator in evaluation of pharmacologic and toxicologic experiment of systemically administered drug.
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