J Korean Ophthalmol Soc.
1988 Apr;29(2):297-302.
Intraocular Infusate with Hemocoagulase for the Control of Bleeding During Vitreous Surgery
- Affiliations
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- 1Department of Ophthalmology, School of Medicine, Kyung-Pook National University, Taegu, Korea.
- 2Department of Biomedical Engineering, School of Medicine, Kyung-Pook National University, Taegu, Korea.
Abstract
- The effects of hemocoagulase in injectable form(hemocoagulating enzymatic fraction of South American snake Botrops Jararaca venom provided by Ravizza) on the control of intraocular bleeding during vitreous surgery were evaluated in rabbit eyes. Intraocular infusion solution with hemocoagulase(1 NIH thrombin unit/100 ml BSS) significantly reduced the bleeding time to 33.2 +/- 9.7 seconds. Electroretinogram b-wave and electroretinogram c-wave showed no abnormality. Infusate with hemocoagulase appeared to be a favorite agent for the control of intraocular bleeding during viteous surgery.
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