J Korean Ophthalmol Soc.  1982 Sep;23(3):805-809.

A Case of Retinoblastoma Associated with Secondary Glaucoma

• Whang SK
• Lew HM
• Kim HB

Abstract

Retinoblastoma is a rare, congenital, malignant tumor that arises from the retina. It is the most common intraocular tumor occurring during childhood. Retinoblastoma usually remains unnoticed until it has advanced far enough to produce a white pupil. But it may manifest as a painful, red, tearing eye due to secondary glaucoma. The most common mechanism inducing secondary glaucoma in retinoblastoma is neovascularization of iris with peripheral anterior synechiae formation. The next common mechanism is massive exudative retinal detachment causing pupillary block and angle closure. Uveitis and/or necrotic tumor tissue in anterior chamber acn contribute to the development of secondary glaucoma. A 9 month old Korean boy was seen to have somewhat enlarged cornea with massive exudation in anterior chamber OS. Intraocular pressure was 27.4 mmHg OS. The C-T scan was done because of hazy media OS. and showed calcification within left eye. Left eye was enucleated and found to have retinoblastoma which was confirmed microscopically.

MeSH Terms

Anterior Chamber
Cornea
Glaucoma*
Humans
Infant
Intraocular Pressure
Iris
Male
Pupil
Retina
Retinal Detachment
Retinoblastoma*
Tears
Uveitis