J Korean Ophthalmol Soc.  1979 Sep;20(3):273-281.

Experimental Studies of Effects of Ginseng and Steroids on Pneumococcal Endophthalmitis in Rabbits eyes

• Rim YS

Abstract

The experimental endophthalmitis was obtained by the injection of pneumococcus into the anterior chamber of the rabbit's eyes and the effects of ginseng and steroids were observed. In one group, ginseng extract (50 mg/kg) was injected intraperitoneally for 6 days. In another group, dexamethasone (0.1 mg/kg) was injected intramuscularly and prednison(R) ophthalmic ointment used topically for 6 days. All groups were treated with atropine and colimycin-T@ ophthalmic ointment topically for 8 days. The eyes were examined clinically and histopathologically. The characteristic pictures of changes of peneumococcal endophthalmitis were stmrnal edema of the cornea by slit lamp biomicroscopic examination. The resuns were as follows: 1. In ginseng injection group, the stromal edema of cornea was more aggravated than control group. 2. In steroids injection group, the stromal edema of cornea was more aggravated than control group. 3. There was no notable difference between the changes in the ginseng injection group and steroids injection group.

MeSH Terms

Anterior Chamber
Atropine
Cornea
Dexamethasone
Edema
Endophthalmitis*
Panax*
Rabbits*
Steroids*
Streptococcus pneumoniae
Atropine
Dexamethasone
Steroids