J Korean Soc Echocardiogr.
2005 Mar;13(1):10-15.
Impact of Geometry of Left Ventricular Outflow Tract on Left Ventricular Diastolic Transmitral Inflow Doppler Patterns
- Affiliations
-
- 1Department of Cardiology, Ajou University School of Medicine, Suwon, Korea. shinjh@ajou.ac.kr
Abstract
- BACKGROUND
Aging is an important factor to determine transmitral inflow velocity pattern. Cardiac geometry such as left ventricular (LV) volume, mass and left ventricular outflow tract (LVOT) was also changed with age. The aim of this study was to assess the impact of geometric change of LVOT on transmitral inflow velocity pattern excluding a factor of age.
METHODS
Healthy 115 (61 men, 37+/-15 years) individuals were enrolled. Echocardiography was performed to measure LV mass, thickness, left atrial (LA) size, aortoseptal angle (ASA), early (E) and late (A) transmitral inflow velocity, and deceleration time (DT). ASA was measured at mid-diastole in apical long-axis view according to a method as the open angle between the edge of the interventricular septum and axis perpendicular to the aortic annulus. The relation between transmitral inflow velocity pattern and LV geometric parameters was analyzed by regression analysis.
RESULTS
Simple regression analysis demonstrated a significant correlation between transmitral inflow parameters with age and geometric parameters (ASA, LA size and LV mass index). Multiple regression analysis, taking into consideration age, ASA, LA size and LV mass index showed that only age was an independent predictor for E, A, DT, and E/A ratio (r2=0.210, Beta coefficient (beta)=0.459, p<0.001;r2=0.427, beta=0.654, p<0.001;r2=0.227, beta=-0.476, p<0.001;r2=0.436, beta=-0.661, p<0.001, respectively). But, excluding age, ASA was an independent predictor for E, A, DT, and E/A ratio (r2=0.151, beta=0.389, p<0.001;r2=0.294, beta=0.542, p<0.001;r2=0.227, beta=-0.476, p<0.001;r2=0.260, beta=0.509, p<0.001, respectively).
CONCLUSION
ASA, a parameter of LVOT geometry, might be an important factor related to transmitral inflow velocity pattern excluding a factor of age.
Keyword
- Full Text Links
-
- Actions
-
Cited
- CITED
-
- Close
- Share
-
- Similar articles
-
- The Influence of the Left Ventricular Geometry on the Left Atrial Size and Left Ventricular Filling Pressure in Hypertensive Patients, as Assessed by Echocardiography
- Assessment of Left Ventricular Diastolic Pressures with Pulmonary Venous Flow and Transmitral Inflow by Doppler Echocardiography
- Reconstruction of the Transmitral Flow Rate Curve with M-Mode,2-Dimensional and Doppler Echocardiography -Validation Study-
- Huge Multilobulated Left Ventricular Outflow Tract Pseudoaneurysm Presenting with Ventricular Tachycardia
- Evaluation of Left Ventricular Diastolic Function by Measurement of Posterior Myocardial Wall Velocity
