J Korean Soc Plast Reconstr Surg.  2006 Mar;33(2):193-197.

Incidence and Risk Factors of Pulmonary Thromboembolism in Pedicled TRAM Breast Reconstruction

• Lee SH
• Lee TJ
• Eom JS
• Son BH
• Ahn SH
• Lee SD

Abstract

Pulmonary thromboembolism is often clinically silent and difficult to diagnose, and can be fatal to patients with belated treatment. This complication is seen in patients who underwent TRAM breast reconstruction. Multiple factors are involved in this disease such as the presence of malignancy itself, major surgery and therapy-related interventions. TRAM surgery is a lengthy procedure involving mastectomy, flap surgery and abdominoplasty. The purpose of this study is to evaluate the incidence and the correlation between presurgical risk factors(BMI and age) of symptomatic pulmonary thromboembolism after TRAM surgery and the incidence. From July 2001 to March 2005 a total of 384 pedicled TRAM reconstruction of breast was performed in 382 patients at Asan Medical Center. The average of Body mass index was 21.9kg/m(2) and mean age of the patients was 37.9 years old. We diagnosed symptomatic pulmonary thromboembolism using ventilation/perfusion lung scan and pulmonary embolism computed tomography. Incidence of in-hospital symptomatic pulmonary thromboembolism was 1.3%. BMI and age showed no significant statistical relationship to pulmonary thromboembolism. But the incidence of symptomatic pulmonary thromboembolism in obese patients (BMI>25) was 3.75%. According to the guideline of the 7th American College of Chest Physicians Consensus Conference on Antithrombotic and Thrombolytic Therapy, the incidence of 3.75% was classified as high risk group. The prevention of pulmonary thromboembolism should be considered in cases of obese patients with low molecular weight heparin(BMI>25).

Keyword

TRAM flap; Breast reconstruction; Pulmonary thromboembolism

MeSH Terms

Abdominoplasty
Body Mass Index
Breast*
Chungcheongnam-do
Consensus
Female
Humans
Incidence*
Lung
Mammaplasty*
Mastectomy
Molecular Weight
Pulmonary Embolism*
Risk Factors*
Thorax
Thrombolytic Therapy