J Korean Rheum Assoc.  2004 Dec;11(4):442-446.

Seizure Attacks in a Diffuse Systemic Sclerosis Patients

Affiliations
  • 1Departments of Internal Medicine, College of Medicine, Seoul National University, Seoul, Korea. leb7616@snu.ac.kr
  • 2Departments of Neurology, College of Medicine, Seoul National University, Seoul, Korea.

Abstract

Systemic sclerosis is a rare, autoimmune, connective tissue disorder which involves skin and other internal organs. However, central nervous system involvement including seizure, is a very rare event. This 29-year-old woman experienced repeated episodes of typical generalized tonic clonic seizure. T2 weighted and flare images of magnetic resonance image showed a mass-like high signal intensity lesion in the left temporal lobe. Atypical spikes and waves were present in a eclectroencephalogram. Her seizure episodes were controlled with anticonvulsants, corticosteroids and immunosuppresants. We report a rare case of systemic sclerosis which showed central nervous system involvement.

Keyword

Scleroderma; Systemic; Seizures; Magnetic resonance imaging

MeSH Terms

Adrenal Cortex Hormones
Adult
Anticonvulsants
Central Nervous System
Connective Tissue
Female
Humans
Magnetic Resonance Imaging
Scleroderma, Diffuse*
Scleroderma, Systemic
Seizures*
Skin
Temporal Lobe
Adrenal Cortex Hormones
Anticonvulsants
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