J Korean Radiol Soc.  1998 Nov;39(5):959-963. 10.3348/jkrs.1998.39.5.959.

The Value of Intrarenal Resistive Index in Autosomal Dominant Polycystic Kidney Disease

Affiliations
  • 1Department of Radiology, Kangbuk Samsung Hospital, Sungkyunkwan University, College of Medicine.
  • 2Department of Nephrology, Kangbuk Samsung Hospital, Sungkyunkwan University, College of Medicine.

Abstract

PURPOSE: The purpose of this study was to determine the value of the intrarenal resistive index (RI),measured by Doppler sonography, in order to assess intrarenal vascular resistance in autosomal dominant polycystickidney disease (ADPKD) patients.
MATERIALS AND METHODS
In 26 patients with ADPKD, RI was measured by Dopplersonography and correlated with the presence of hypertension, renal function (creatinine clearance) and anatomicalrenal severity index (RSI), thus indicating renal morphologic abnormalities during B-mode sonography .
RESULTS
RI was significantly higher in 18 hypertensive ADPKD patients (0.64+/-0.65) (Mean+/-1SD; range: 0.52-0.74) than ineight normotensive patients (0.59+/-0.50) ( 0.48-0.64) (p<0.05). Statistically significant inverse correlation wasfound between RI values and creatinine clearance (r=-0.45, p<0.05), and statistically significant correlation wasfound between RI values and RSI, indicating the degree of renal parenchymal involvement.
CONCLUSION
RIcorrelates with the development of hypertension, renal function and renal morphologic abnormality scoring by RSIduring B-mode Doppler sonography, and measured in this way may thus be used to assess renal vaseular resistance inADPRD patients.

Keyword

Kidney, US; Kidney, cysts; Ultrasound (US); Doppler Studies

MeSH Terms

Creatinine
Humans
Hypertension, Renal
Polycystic Kidney, Autosomal Dominant*
Vascular Resistance
Creatinine
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