J Korean Soc Pediatr Nephrol.
2003 Apr;7(1):96-102.
A Case of Continuous Venovenous Hemodiafiltration in the Treatment of Neonatal Hyperammonemia Due to Methylmalonic Acidemia
- Affiliations
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- 1Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. yspark@amc.seoul.kr
Abstract
- Acute hyperammonemia is a medical emergency in the newborn. Efficient, prompt removal of serum ammonia is essential in preventing irreversible brain damage in order to prevent the profound central nervous system dysfunction due to hyperammonia. We report a case of 2.3 kg, 5-day old girl with methylmalonic acidemia who presented with severe hyperammonemia and was successfully treated with continuous venovenous hemodiafiltration(CVVHDF). CVVHDF is an effective and safe method of ammonia removal in the newborn.
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