J Korean Soc Ther Radiol.  1989 Jun;7(1):51-58.

The Role of Postoperative Adjuvant Radiation Therapy in the Management of Adenocarcinoma of the Colon: A review of 21 Patients

Affiliations
  • 1Department of Radiation Oncology, Busan National University Hospital, Busan, Korea.
  • 2Department of Radiation Oncology, College of Medicine, Yonsei University, Seoul, Korea.

Abstract

From March 1970 to December 1984, treatment results of 21 patients treated initially with curative surgery for adenoarcinoma of the colon and referred to the Department of Radiation Oncology, College of Medicine, Yonsei University, were analyzed retrospectively. Thirteen of 21 patients who were considered to be at high risk (i.e, stage B2 or above), received postoperative adjuvant radiation therapy. However, 2 of 13 patients did not complete their courses of radiotherapy as planned because of poor tolerance to radiotherapy or patient's refusal and were excluded from this study. Remaining 8 of 21 patients who did not receive postoperative radiotherapy, presented with recurrence at the time of referral and treated for palliation. In 11 patients who finished postoperativc radiotherapy, overall local failure rate was 9%(1/11) and the 5 year actuarial survival rate was 55%. Local failure rates by stage were 0(0/4), 14%(1/7) for stage B2+B3, C1+C2+C3 respectively and 0(0/2), 17%(1/6), 0(0/3) for stage C1, B2+C2, B3+C3 respectively.

Keyword

Adenocarcinoma of colon; Adjuvant postoperative radiotherapy; local failure

MeSH Terms

Adenocarcinoma*
Colon*
Disulfiram
Humans
Radiation Oncology
Radiotherapy
Recurrence
Referral and Consultation
Retrospective Studies
Survival Rate
Disulfiram
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