Results of Radiation Therapy in Early Glottic Cancer

Ahn, Sung Ja; Chung, Woong Ki; Nam, Taek Keun; Nah, Byung Sik

Abstract

A retrospective analysis was undertaken for 22 patients with early glottic cancer (T1N0M0;17, T2N0M0;5) who completed curative radiotherapy at the Department of Therapeutic Radiology, Chonnam University Hospital between November 1985 and December 1990. Median follow-up period was 39 months. The 3 year actuarial survival rate of T1,T2 was 81% and 80%, respectively. Three patients(13%) shewed second malignant tumors and the site of the new primary was esophagus in two patients and lung in the other one. They were excluded from the local control analysis. The local control rate of T1,T2 group was 66% and 50%, respectively. The surgical salvage rate and the ultimate local control rate of T1 group was 80%(4/5) and 93%, and that of T2 group was 100%(2/2) and 75%, respectively. The local control rates of T1 stage were evaluated according to the various parameters. The local control rate of the superficial and exophytic lesion was better than that of the ulcerative and infiltrative one, and the involvement of anterior commissure was not seemed to be adverse prognostic factor. But the protracted treatment time showed the adverse effect on the local control of the disease. All of the eleven patients controlled by primary radiation therapy have maintained their voice well without any significant complication.