J Korean Soc Ther Radiol.  1995 Sep;13(3):225-232.

Malignant Fibrous Histiocytoma of the Maxilla: Report of A case

Affiliations
  • 1Depatment of Therapeutic Radiology Chosun University Medicine College, Kwangju, Korea.
  • 2Depatment of Oral & Maxilloiacial Surgery, Chosun University College, Kwangju, Korea.

Abstract

Malignant fibrous histiocytoma(MFH) of the maxilla is a rare malignant bone tumor. Seven percents of all MFH occur in the head and neck. Approximately 12% of these tumors occur in the maxilla. Local recurrence or distant metastasis was reported in 55% of cases of maxillary MFH. The mean survival time of 30 months was reported from a review of 14 MFHs in he masxilla, mandible and oral soft tissues. MFH of the maxilla is best treated surgically but radical neck dissection dose not appear to be indicated unless there is clinical evidence of lymph node metastases. Although the use of radiation therapy for head and neck MFH has not been studied for a series of cases, individual cases of regression or histological change have been reported. Other authors have reported numbers of cases who received radiation therapy without benefit. Response to combination chemotherapy has been reported in 33% of 23 patients with recurrent or metastatic MFH. We report here a case of MFH occurring in the maxilla with a review of literature about the clinical behavior and treatment of these lesions.

Keyword

malignant Fibrous Histiocytoma; Radiation Therapy; Maxilla

MeSH Terms

Drug Therapy, Combination
Head
Histiocytoma, Malignant Fibrous*
Humans
Lymph Nodes
Mandible
Maxilla*
Neck
Neck Dissection
Neoplasm Metastasis
Recurrence
Survival Rate
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