J Korean Neurotraumatol Soc.  2010 Jun;6(1):43-47. 10.13004/jknts.2010.6.1.43.

Relationship between the Level of Fibrinogen and the Signal Density on Brain Computed Tomography in the Chronic Subdural Hematoma

• Son WS
• Park SH
• Kang DH
• Park J
• Sung JK
• Hwang SK

• KMID: 2192363
• DOI: http://doi.org/10.13004/jknts.2010.6.1.43

Abstract

OBJECTIVE
The purpose of this study was to evaluate the relationship between fibrinogen levels and computed tomography (CT) findings in patients who had chronic subdural hematomas (CSDHs).
METHODS
The study group was composed of 12 consecutive patients who had CSDH between January and December 2006. Patients with CSDH were divided on the basis of CT findings into group A (layering, mixed type) and group B (low, iso type). We performed surgery and obtained a sample from the subdural hematoma for measurement of the concentration of fibrinogen.
RESULTS
The mean level of fibrinogen was 57.3 mg/dL in group A, and in <25 mg/dL group B. The concentration of fibrinogen was significantly higher in the layering and mixed type group than in the low and iso type group (p=0.003).
CONCLUSION
The layering, mixed type of CSDH demonstrated higher concentrations of fibrinogen in subdural hematomas than in low, iso type patients.

Keyword

Chronic subdural hematoma; Fibrinogen; Computed tomography

MeSH Terms

Brain
Fibrinogen
Hematoma, Subdural
Hematoma, Subdural, Chronic
Humans
Fibrinogen

Figure

• 

  FIGURE 1 Computerized tomography scans demonstrate four types of chronic subdural hematoma: mixed density (A), layering (B), low density (C), iso density (D).

• 

  FIGURE 2 Graph showing the levels of fibrinogen in chronic subdural hematomas. The concentration of fibrinogen was significantly higher in the layering and mixed type group than in the low and iso type group (p=0.003).

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