J Korean Neurosurg Soc.  2014 Mar;55(3):164-166. 10.3340/jkns.2014.55.3.164.

Ganglioglioma in Brainstem : Case Report and a Review of Literatures

• Kim SD
• Kim JH
• Lee CY
• Kim HW

• KMID: 2191084
• DOI: http://doi.org/10.3340/jkns.2014.55.3.164

Abstract

Ganglioglioma is an infrequent tumor of the central nervous system (CNS); mostly supratentorial region. But, they can occur anywhere in the central nervous system such as brainstem, cerebellopontine angle (CPA), thalamus, optic nerve and spinal cord. Although it occurs rarely, ganglioglioma should be included in the differential diagnosis of a posterior fossa mass because early recognition is important for treatment and patient counseling.

Keyword

Ganglioglioma; Brainstem

MeSH Terms

Brain Stem*
Central Nervous System
Cerebellopontine Angle
Counseling
Diagnosis, Differential
Ganglioglioma*
Humans
Optic Nerve
Spinal Cord
Thalamus

Figure

• 

  Fig. 1 MRI findings. A : T2-weighted images showing slightly high signal intensity mass on the dorsal surface of brainstem and high cervical cord. B and C : T1-weighted images showing an isointensity with a well-enhanced mass.

• 

  Fig. 2 Photomicrographs of the tumor pathology. Ganglioglioma composed of astrocytes and ganglion cells with dysplastic, binucleated neuron (H-E, ×400).

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  Fig. 3 Immunohistochemical staing. A : Neurons reactive for Chro-magranin (×400). B : Glial cells reactive for GFAP (×200).

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