J Korean Neurosurg Soc.  1999 Oct;28(10):1479-1484.

Risk Factors of Late Post-traumatic Seizure

• Lee SW
• Kim SH
• Chung ES
• Bae JH
• Choi BY
• Cho SH

Abstract

OBJECTIVE
The goal of our study was to identify and evaluate risk factors for late post-traumatic seizure.
METHODS
This study is a retrospective clinical analysis of 52cases of late post-traumatic seizures among 1472 head injury patients treated in our institute from July 1986 to June 1996 and at least followed up over 2 years after head injury.
RESULTS
1) The incidence of late post-traumatic seizure was 3.5% of patients treated for head injury. 2) The factors affecting the incidence of late post-traumatic seizure were initial low Glasgow coma scale(3-8), subdural hematoma, depressed skull fracture(p<0.05). 3) Skull fracture located in temporal area showed higher incidence of late post-traumatic seizure(p<0.05).
CONCLUSION
The risk factors for post-traumatic seizure are subdural hematoma, initial low Glasgow coma scale, depressed skull fracture and temporal bone fracture. Both newer antiepileptic drugs and therapies aimed at prevening the brain damage that underlies the development of seizures need to be studied to find an effective way of preventing late post-traumatic seizure through prospective study.

Keyword

Late post-traumatic seizure; Glasgow coma scale; Subdural hematoma; Depressed skull fracture; Temporal bone fracture

MeSH Terms

Anticonvulsants
Brain
Coma
Craniocerebral Trauma
Epilepsy, Post-Traumatic*
Glasgow Coma Scale
Hematoma, Subdural
Humans
Incidence
Retrospective Studies
Risk Factors*
Seizures
Skull
Skull Fracture, Depressed
Skull Fractures
Temporal Bone
Anticonvulsants