J Korean Geriatr Soc.  2012 Dec;16(4):233-236. 10.4235/jkgs.2012.16.4.233.

Risedronate-related Localized Amnesia in an Elderly Patient with Osteoporosis

Affiliations
  • 1Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea. belong.cho@gmail.com

Abstract

Osteoporosis is the most common metabolic bone disease that results in an increased risk of fragility fractures. Bisphosphonates are commonly used in the treatment of osteoporosis. Concerns about their association with several possible adverse effects have been raised. Here, we experienced a rare case regarding a 63-year-old female patient who had localized amnesia related to once-monthly oral risedronate. A clear cause-and-effect relationship between the treatment of risedronate and this event has not been established and the mechanism behind the adverse effect is unknown. As clinical uses of bisphosphonates continue to expand, clinicians should be aware of the rare but potential adverse effects associated with bisphosphonates including neuropsychiatric problems.

Keyword

Risedronate; Osteoporosis; Amnesia

MeSH Terms

Aged
Amnesia
Bone Diseases, Metabolic
Diphosphonates
Etidronic Acid
Female
Humans
Osteoporosis
Risedronate Sodium
Diphosphonates
Etidronic Acid
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