J Korean Geriatr Psychiatry.  2007 Jun;11(1):40-43.

Prescription Pattern of Risperidone and Olanzapine for Elderly Psychiatric Inpatients in a Naturalistic Setting

• Lim HK
• Choi EH
• Lee YR
• Oh K
• Pae CU
• Lee C
• Paik IH
• Lee CU

Abstract

Several studies have reported that either risperidone or olanzapine is effective and tolerable in the elderly patients with psychotic symptoms. However, there is a lack of clinical data of risperidone and olanzapine prescription for elderly patients in the Aisan population. We reviewed retrospectively the medical records of risperidone (n=112) and olanzapine (n=96) treated patients older than age 60 who were admitted to a university-affiliated hospital between October 2005 and August 2006. The mean daily dose of risperidone was 3.4+/-1.5 mg and olanzapine, 8.8+/-5.6 mg, respectively. The response rate on the CGI (much and very much improved) appeared to be 67.4% in the risperidone group and 70.8% in the olanzapine group, respectively. Adverse events were reported in 48.2% in the risperidone group and 46.9% in the olanzapine group, without serious adverse events, respectively. This study showed that either risperidone or olanzapine would be effective and tolerable in elderly patients with psychotic symptoms and that provides similar results to those reported from western countries.

Keyword

Olanzapine; Risperidone; Old age; Psychosis

MeSH Terms

Aged*
Humans
Inpatients*
Medical Records
Prescriptions*
Psychotic Disorders
Retrospective Studies
Risperidone*
Risperidone