J Korean Med Assoc.  2006 Jan;49(1):63-69. 10.5124/jkma.2006.49.1.63.

Treatment of Acne

• Whang KU

• KMID: 2184637
• DOI: http://doi.org/10.5124/jkma.2006.49.1.63

Abstract

Acne vulgaris is a self-limited disease, seen primarily in adolescents. Most cases of acne are pleomorphic, presenting various lesions consisting of comedones, pustules, and nodules. Although it has been traditionally classified as a disease of the sebaceous gland, it actually involves the pilosebaceous unit. There are four major principles in the treatment of acne: (1) correct the altered pattern of follicular keratinization; (2) decrease the sebaceous gland activity; (3) decrease the follicular bacterial population; and (4) produce anti-inflammatory effect. The natural course of acne varies greatly, and therefore, the determination of the therapeutic efficacy of medications for the treatment of acne is far from being simple.

Keyword

Acne; Pilosebaceous Unit; Comedone; Retinoid

MeSH Terms

Acne Vulgaris*
Adolescent
Humans
Sebaceous Glands

Figure

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  Figure 1 Pathophysiology of ance

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