J Korean Neurol Assoc.  2015 Aug;33(3):183-185. 10.17340/jkna.2015.3.8.

Ceftazidime-Induced Nonconvulsive Status Epilepticus

Affiliations
  • 1Department of Neurology, Eulji General Hospital, Eulji University College of Medicine, Seoul, Korea. sss331@eulji.ac.kr

Abstract

Ceftazidime is a widely used third-generation cephalosporin. We report a case of ceftazidime-induced nonconvulsive status epilepticus in a patient with renal failure. A 56-year-old man experienced the gradual development of altered mentation after a diabetic foot ulcer was treated with ceftazidime. Rhythmic sharply contoured triphasic waves were evident in all electroencephalography leads. The clinical and electrographical seizures ceased after introducing antiepileptic drugs and discontinuing ceftazidime. This case demonstrates that altered mentality and nonconvulsive status epilepticus can be caused by ceftazidime in patients with renal dysfunction.

Keyword

Ceftazidime; Nonconvulsive status epilepticus

MeSH Terms

Anticonvulsants
Ceftazidime
Diabetic Foot
Electroencephalography
Humans
Middle Aged
Renal Insufficiency
Seizures
Status Epilepticus*
Ulcer
Anticonvulsants
Ceftazidime
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