J Korean Androl Soc.
1991 Dec;9(2):99-104.
Effect of treatment in men with idiopathic hypogonadotropichypodonadism
- Affiliations
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- 1Department of Urology, Yonsei University College of Medicine, Seoul, Korea.
Abstract
- Thirteen men with idiopathic hypogonadotropic hypogonadism were treated with androgen (group A : 6 cases), hCG alone or hCG/hMG (group B : 5 cases), or GnRH (group C : 2 cases). The effects according to the treatment modality were compared. After treatment, the penile size and pubic hair were improved on group A. The plasma testosterone, testicular size, penile size, and pubic hair were improved on group B and C. On semen analysis all 5 cases except one who showed oligoasthenozoospermia before treatment were still seen azoospermia in group A, but 2 of 3 cases in group B and 2 of 2 cases in group C were improved. Thus, if only virilization is desired, either androgen therapy, hCG/hMG, or GnRH therapy may be used. If fertility is desired, however, either hCG/hMG or GnRH administration is required. And GnRH treatment seems probably more desirable than hCG/hMG.
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