J Gynecol Oncol.  2010 Mar;21(1):59-61. 10.3802/jgo.2010.21.1.59.

Metastasis to the ovaries from transitional cell carcinoma of the bladder and renal pelvis: a report of two cases

• Lee M
• Jung YW
• Kim SW
• Kim SH
• Kim YT

• KMID: 2173517
• DOI: http://doi.org/10.3802/jgo.2010.21.1.59

Abstract

Ovarian metastases from a primary urinary tract carcinoma are extremely rare. This can be difficult to distinguish from transitional cell carcinomas (TCC) of ovarian origin because of histologic similarity. A 65-year-old woman who was diagnosed with renal pelvis TCC 4 months prior was referred for evaluation of a left ovarian mass. A 47-year-old woman who underwent radical cystectomy due to bladder TCC 1 year ago was referred because of a right ovarian mass. Both patients underwent a bilateral salpingo-oophorectomy. The tumor cells had morphology identical to those of the primary urinary tract tumors. Gynecologic oncologists should consider metastatic TCC of the ovary from urinary tract origin, as well as breast, and gastrointestinal tract origins.

Keyword

Transitional cell carcinoma; Ovarian metastasis

MeSH Terms

Aged
Breast
Carcinoma, Transitional Cell
Cystectomy
Female
Gastrointestinal Tract
Humans
Kidney Pelvis
Middle Aged
Neoplasm Metastasis
Ovary
Urinary Bladder
Urinary Tract

Figure

• 

  Fig. 1 (A) Gross appearance of the right kidney and ureter showing TCC of the renal pelvis. (B) Gross appearance of the left ovary showing a solid rubbery mass that nearly replaces the ovarian parenchyma. (C) Microscopic finding of transitional cell carcinoma of the renal pelvis (H&E, ×100). (D) Metastatic transitional cell carcinoma of the ovary (H&E, ×200).

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